A Missing Protein May Contribute to Autism: New Study

Lack of a protein that aids in the development of brain synapses may be partly responsible for autism, according to scientists at the Picower Institute of the Massachusetts Institute of Technology (M.I.T.).  This latest research was research recently published in the journal Neuron.

According to scientists, malfunction of a kinase (an enzyme that changes proteins) known as Cdk5, which plays a key role in the formation of synapses, appears to be associated with autism.  Malfunctions related to Cdk5 have previously been implicated in neurodegenerative diseases such as Alzheimers.  The recently published Picower study also offers the first molecular explanation of exactly how this particular kinase promotes synapse development. 

Study authors caution that there are still many unknown variables regarding the onset of autism, but that this research contributes to a growing body of research that suggests the development of brain synapses is a key component of many behavioral and psychiatric disorders, including autism. 

Previously on the DC Metro Area Medical Malpractice Law Blog, we have posted articles related to:

  • Indications that your child could have a Pervasive Developmental Disorder (PDD)
  • Evidence that the CDC suppressed evidence that could link vaccines to autism
  • A new study linking infant television exposure to behavior in children

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